Increasing Antimicrobial Resistance and Narrowing Therapeutics in Typhoidal Salmonellae

Increasing antimicrobial resistance and narrowing therapeutics in typhoidal salmonellae.

Multidrug-resistant typhoid fever (MDRTF) is a major public health problem in developing countries and is an emerging problem in the developed world. Because of the difficulties in preventing typhoid by public health measures or immunization in developing countries, great reliance is placed on antimicrobial chemotherapy. The treatment should commence as soon as the clinical diagnosis is made ra...

Increasing Ceftriaxone Resistance in Salmonellae, Taiwan

In Taiwan, despite a substantial decline of Salmonella enterica serotype Choleraesuis infections, strains resistant to ciprofloxacin and ceftriaxone persist. A self-transferable bla(CMY-2)-harboring IncI1 plasmid was identified in S. enterica serotypes Choleraesuis, Typhimurium, Agona, and Enteritidis and contributed to the overall increase of ceftriaxone resistance in salmonellae.

In vitro susceptibility of typhoidal Salmonellae against newer antimicrobial agents: a search for alternate treatment options.

OBJECTIVES To determine the minimum inhibitory concentrations (MICs) of ceftriaxone, azithromycin, pefloxacin, cefipime and imipenem for Salmonella Typhi (S. Typhi) and Paratyphi. METHODS One hundred and fifty four isolates of Salmonella Typhi and S. Paratyphi A, B and C growing in blood culture were selected. MICs of ceftriaxone, azithromycin, pefloxacin, cefipime and imipenem were performed...

Quinolone resistance in non-typhoidal Salmonellae isolated from patients having primary extra-intestinal infections.

Drug Resistance Patterns of Typhoidal and Non-typhoidal Salmonella Species in Hamadan

ABSTRACT The epidemiological studies indicate that the incidence of salmonellosis is increasing throughout the world. The uncontroled and unappropriate usage of antibiotics has been caused multi - drug resistance in these organisms, in recent years. In a cross-sectional descriptive study, 204 strains of typhoidal salmonella (T.S) and 114 strains of non-typhoidal salmonella (N.T.S) were exami...